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  1. #1
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    Default Zirtek (Cetirizine Hydrochloride)?

    Has anyone any experience of giving Zirtek (which I think is the brand name for cetirizine hydrochloride) to horses for allergies?
    Or any other antihistamines?
    Thanks in advance.
    S

  2. #2
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    ITs the same stuff that is in Piriton tablets - there was a post on this last week I think - a lot of positive outcomes if I remember correctly.

  3. #3
    Veteran noblesteed's Avatar
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Be careful. I have taken it myself for my hayfever and it made me dizzy and sick. Like a migraine! It's common for people to have adverse reactions to it, so i'd monitor your horse carefully if you give it cetirizine!
    Although I may just be a freak of nature...

  4. #4

    Default Re: Zirtek (Cetirizine Hydrochloride)?

    the hayfever tablets which contain cetirizine hydrochroride usually have the 'can cause drowsiness' warning, whereas the 'non-drowsy' ones contain Loratadine. I don't know if this would make a difference if giving them to an equine?

  5. #5
    Old nag Slinkyunicorn's Avatar
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Quote Originally Posted by noblesteed View Post
    Be careful. I have taken it myself for my hayfever and it made me dizzy and sick. Like a migraine! It's common for people to have adverse reactions to it, so i'd monitor your horse carefully if you give it cetirizine!
    Although I may just be a freak of nature...
    It cetainly is not common for people to have adverse reactions to it - it is the most widely sold antihistamine/anti aleergen in the world - part of the reason for that is that it has been shown to work better than the others and with fewer side effects, drug interactions etc than the others as it is metabolised differently than other antihistamines. Side effects/adverse reactions are always possible as everyone is different nut you can not say they are common - the drug would not be licensed it they were 'common'.
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    Old nag Slinkyunicorn's Avatar
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Quote Originally Posted by LeneHorse View Post
    the hayfever tablets which contain cetirizine hydrochroride usually have the 'can cause drowsiness' warning, whereas the 'non-drowsy' ones contain Loratadine. I don't know if this would make a difference if giving them to an equine?
    All anithistamines - including loratadine contain warnings about drowsiness, they have to as peoples metabolism makes them respond to the drugs in different ways. The advice is to always take once daily anti histamines at night - that way if you are more susceptible to drowisness it won't matter as you will be asleep anyway - the same would apply to horses. Cetirizine as a molecule is the 'cleanest' molecule with fewer side effects/interactions than loratadine as it is metabolised differently.
    *If lost please to return to Sweet FA or The Bar - thankies *

  7. #7
    Veteran JoG's Avatar
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    It's not the same as Piriton - that is Chlorphenamine and that can definitely make you drowsy - it is the anti-histamine used for treating severe allergic or anaphylactic reactions in humans....it is the only one I've ever given to a horse

    Zirtek (cetirizine) is in Piriteze which claims to be non-drowsy. I did a google and found a research paper which suggests that you need to give a horse 0.2-0.4mg per kg of body weight to have an effect

    For a 500kg horses that would be 100-200mg, or about 10-20 Zirtek tablets could get pricey!!
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Thanks for your help.
    I guess all drugs have side effects, and can affect different individuals in differing ways; the only way I'll find out is to give her them to her and see.
    I'd read the study regarding induced skin inflammation and the effects of various anti-histamines, and that's what made me think that cetrizine hydrochloride may be suitable for my girl's skin problems.
    She's probably about 500 - 550kg (no access to a weigh bridge), so I reckon I'll start her on one morning and night, then after a couple of days increase it to a max of 10 daily.
    If her skin doesn't improve then, I'll have to think of something else.
    S

  9. #9
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Quote Originally Posted by Roody2 View Post
    ITs the same stuff that is in Piriton tablets - there was a post on this last week I think - a lot of positive outcomes if I remember correctly.
    No it isn't, I think you're thinking of Piriteze.
    The active ingredient in Piriton is chlorphenamine. Piriton only lasts for 4 hours per dose, which is the drawback IME to giving it to horses.
    I have to take anti-histamines on a regular basis most years and have experimented with just about all of them. I have found that the most effective with fewest side effects is the Piriton liquid. Piriton has been recommended by our vet. We have given 2 of our horses Piriton tablets and have found them effective in that the symptoms were alleviated but there was a 'something not quite right' that we couldn't just identify about the ridden one. Eventually we thought that perhaps it was giving her an unpleasant taste in her mouth, as happens to some people. We have decided that if we need to medicate the horses this year (usually happens if rape pollen blows over from the east) we will try the liquid.
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  10. #10
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    Default Re: Zirtek (Cetirizine Hydrochloride)?

    Quote Originally Posted by Shilasdair View Post
    Thanks for your help.
    I guess all drugs have side effects, and can affect different individuals in differing ways; the only way I'll find out is to give her them to her and see.
    I'd read the study regarding induced skin inflammation and the effects of various anti-histamines, and that's what made me think that cetrizine hydrochloride may be suitable for my girl's skin problems.
    She's probably about 500 - 550kg (no access to a weigh bridge), so I reckon I'll start her on one morning and night, then after a couple of days increase it to a max of 10 daily.
    If her skin doesn't improve then, I'll have to think of something else.
    S
    My girl lives on cetrizine hydrochloride 10mg, for her pollen and dust allergies. I've also used them on other unknown allergies, when a horse has had hives etc.
    1 tablet wont make a difference. I get mine from my vet (they are far cheaper buying from the vet about 36 for 100 boxes of 30!), my girl weighs about 500kg, and she has a max dose of 50 tablets a day (split into 2 meals). They have never made her drowsy. Now I'm not sugesting you feed your horse the max dose, but it'll give you an idea of whats safe. So you can be reasured that your not going to overdose her. Generally my girl gets a min of 10 a day (vet says less for her weight, wont have an effect) And then I dose her up, as and when needed

    Jill

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